Clinical and preclinical research on Ultracol and PDO microspheres, each with a short plain-language summary and a link to the original.
At week 8, sunken volume improved 22.68% with PDO vs 7.69% with a hyaluronic acid filler.
Giang et al. · 31 participants, aged 20–59, split-face
About 20% smaller pore area and significantly denser dermis vs baseline.
Trinh T. T. T. et al. · 31 participants, aged 20–59, split-face
PDO produced the most active new type III collagen formation, with better-organised collagen bundles than PLLA.
Bernardo R. T. R. et al. · 16 laboratory rats, 4 groups
Better facial projection and contour, shallower nasolabial folds and a lifted malar area after a single session.
Amin M. et al. · 20 patients, aged 40–80
Dermal density rose from 11.04% to 14.72% after 3 sessions and was still 13.69% at 8 months.
KCAC, Korean Skin Clinical Research Center · 3 sessions, 8-month follow-up
Studies marked "manufacturer data" were commissioned by the manufacturer. Results vary between individuals.
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